If your company mass produces anything, you produce defects.  Why is this an important issue?  Simply put, these defects are costing you money; A LOT OF MONEY.  It is not a matter of whether or not cash is indeed flying out the door, but the extent of the loss.

So, can Six Sigma and its inspired methodologies really help?  Frankly, little else can.  Relying upon guesswork, trial & error, and tribal knowledge is just not sufficient, no matter how "scientific" your specific methods may appear.  Without the benefit of statistical evaluations, the best that can be hoped for is a description of what is happening in your manufacturing process at that moment; no inference may be made regarding long-term performance.  This is where Six Sigma methodologies shine.

Six Sigma allows not only for the description of a manufacturing line's momentary performance, not only a statistically-based inference of future performance, but the methodologies allow for a description of what factors could lead to failure.

If you believe that 100% inspection is the cure, then GUESS AGAIN.  There are indeed some great inspection systems available today, but your focus should be on reducing the defects in the first place.  100% inspection is designed to assure you do not send any bad product to your customer, which is a good thing.  However, the products you reject from your manufacturing process are still wasting money.